Page 45 - Portuguese Journal - SPORL - Vol 61. Nº2

Sinonasal malignancies: a retrospective

review of a tertiary center experience

Review Article

Authors Abstract
Objectives: To characterize demographics,
Kaamil Gani presentation, histologic types, treatment and survival
Centro Hospitalar de Lisboa Ocidental, Portugal of patients with sinonasal malignancies diagnosed
at a tertiary hospital center in Portugal.
Tiago Colaço Study design: Retrospective study.
Centro Hospitalar de Lisboa Ocidental, Portugal Material and methods: Review of clinical records
Luís Castelhano from January 2012 to December 2021.
Centro Hospitalar de Lisboa Ocidental, Portugal Results: Nineteen patients were included, with male
predominance (57.9%) and a mean age at diagnosis
Filipe Correia of 66.7 ± 9.8 years. The most common presenting
Centro Hospitalar de Lisboa Ocidental, Portugal symptoms were nasal obstruction and epistaxis
(47.4%). Squamous cell carcinoma was the most
Nélson Gilberto common histologic subtype (21.1%). Primary surgical
Centro Hospitalar de Lisboa Ocidental, Portugal therapy was preferred comparative to nonsurgical
therapy (84.2% VS 15.8%). Nine patients were
Luís Roque dos Reis submitted to external approach, while 7 patients
Centro Hospitalar de Lisboa Ocidental, Portugal
underwent endonasal endoscopic treatment. The
Pedro Escada mean follow-up time was 26.9 ± 20.6 months. Five-
Centro Hospitalar de Lisboa Ocidental, Portugal year overall survival was 53.5% and disease-free
survival was 62.8%.
Conclusion: In this study prognosis was stage and
treatment-dependent, and endoscopic approach
was safe and effective in carefully selected patients.
Keywords: malignant neoplasms; nasal cavity;
paranasal sinus

Introduction
Malignant tumors of the sinonasal tract are
uncommon, comprising less than 1% of all
malignancies and about 3% of head and neck
malignancy .
1, 2
These tumors can arise from a wide variety of
tissues within the nose and paranasal sinuses,
being defined as epithelial or nonepithelial
in origin . Sinonasal malignancies occur
3
predominantly in males, between 50 and 70
years of age .
4
Despite its rarity, in the last decades there has
Correspondence: been significant advances in the diagnosis
Kaamil Gani
gani.kaamil@gmail.com and treatment of sinonasal malignant tumors.
However, survival remains poor . Nasal cavity
5
Article received on November 3, 2022. and paranasal sinus tumors are commonly
Accepted for publication on February 23, 2023.
asymptomatic until they have extended

Volume 61 . Nº2 . June 2023 187