Page 39 - Portuguese Journal - SPORL - Vol 61. Nº2

All data were processed and analyzed using suspicion of having bilateral disease at
the IBM SPSS Statistics software , version 27, the time of diagnosis, and none showed
and statistical significance was set at p<0.05. evidence of cochlear otosclerosis (defined
9
as sensorineural or mixed hearing loss
Informed consent attributable to the disease).
All procedures in this study were performed Table 1 shows the clinical and demographic
according to the regulations established by characteristics of the sample.
the institution’s Clinical Research and Ethics
Committee and the Declaration of Helsinki Comparative analysis of vHIT results
of 1964 of the World Medical Association The mean VOR gains of the horizontal
and its later revisions. The study received semicircular canals in the otosclerosis
a positive opinion and approval from the and control groups were 0.97 and 1.04 for
aforementioned ethics committee, with the right ear and 0.90 and 0.97 for the left
CES no. 57_2022. All participants signed the ear, respectively. This difference was not
informed consent form for the study. statistically significant (Man-Whitney p=0.89
on the right and p=0.76 on the left). The results
Results obtained for the other semicircular canals and
Sample characterization presence of corrective saccades were also not
The final sample contained 24 participants—12 statistically significant (Fisher p=0.32). These
each in the otosclerosis and control groups. results are shown in Table 2.
Twenty-two participants (91.6%) were women, Subsequently, subgroup analysis was
and the mean age of the two groups was 44 performed to compare the VOR gains of the
± 8 years. Six patients (50%) in the otosclerosis three pairs of semicircular canals among
group were under clinical and audiological the control, unilateral otosclerosis, and

Table 1
Clinical and demographic characteristics of the sample (n=24)
Otosclerosis (n=12) Control (n=12)

Female (n, %) 11 (91.6) 11 (91.6)
Age (mean ± SD) 44.4 ± 7.6 44.0 ± 7.9
Bilateral disease (n, %) 6 (50) -
Cochlear otosclerosis (n, %) 0 (0) -
The results are expressed as (n, %) for the categorical variables and (mean ± SD) for the continuous variables.

Table 2
Comparative analysis of vHIT results
Otosclerosis (n=12) Control (n=12) p
VOR Gain Horizontal SCC (R) 0.97 ± 0.07 1.04 ± 0.22 0.89
VOR Gain Horizontal SCC (L) 0.90 ± 0.07 0.97 ± 0.20 0.76
VOR Gain Anterior SCC (R) 1.05 ± 0.33 0.91 ± 0.09 0.32

VOR Gain Anterior SCC (L) 0.85 ± 0.13 0.91 ± 0.08 0.30
VOR Gain Posterior SCC (R) 0.80 ± 0.09 0.86 ± 0.08 0.06
VOR Gain Posterior SCC (L) 0.86 ± 0.22 0.83 ± 0.10 0.21
Presence of corrective saccades 4 (33.33) 2 (16.67) 0.32
vHIT – Video Head Impulse Test; VOR – vestibulo-ocular reflex; SCC – semicircular canal; R – right; L – left; The gain values are expressed
as (mean ± SD), and the presence of corrective saccades is expressed as (n, %).

Volume 61 . Nº2 . June 2023 181