Page 26 - Portuguese Journal - SPORL - Vol 61. Nº2

Figure 8
Evaluation of the response at 16 weeks. ESS, endoscopic sinus surgery

(regardless of the administered biologic (Endoscopic NPS ≥ 4). In our protocol, we
agent) and standardized data collection that opted for the NPS because this scale was used
allows uniform assessment and multicenter for the development of criteria for treatment
prospective and/or retrospective studies. with biologics in patients with CRS with
Nationally and internationally validated scales polyposis by EUFOREA . The main limitation
22
were applied for data collection and eligibility of this scale is that it does not assess polyps
assessment 23-32 . arising in the ethmoidal notch, which does
Endoscopic evaluation of nasal polyps is one not allow comparisons with the results of
of the fundamental steps of the protocol, and trials using a different scale (e.g., the Lildholdt
treatment with biologic agents is indicated scale). To standardize the assessment and
in patients with serious/severe polyposis quantification of nasal polyposis in clinical

Figure 9
Evaluation of the tratmnet response at 24 weeks. ESS, endoscopic sinus surgery

Figure 10
Evaluation of the response to treatment at 12 months.

168 Portuguese Journal of Otorhinolaryngology - Head and Neck Surgery