Page 33 - Revista Portuguesa - SPORL - Vol 61. Nº4

Table 2
Univariate analysis for factors associated with progression to mediastinitis

Control Mediastinitis P
(n=145) (n=20)
Sex 1 Male (n=104) 62,8% 65% 1,00
Age 2 47 ± 16,1 60,2± 16,6 0,007
Diabetes mellitus (n=23) 13,1% 20% 0,487
1
Etiology 1 Idiopathic (n=21) 11% 25% <0,001
Tonsillitis (n=42) 22,8% 45%
Odontogenic (n=86) 56,6% 10%
Others (n=16) 9,7% 20%
Previous antibiotic therapy (n=104) 64,1% 57,9% 0,619
1
Symptom duration in days 3 5 ± 4 4 ± 3 0,224
Laboratory parameters CRP 2 175,86 ± 112,82 256,17 ± 125,03 0,708
Leucocytes 2 15,58 ± 6,08 15,37 ± 6,64 0,642
Neutrophils % 3 79,6 ± 14 87 ± 7,1 0,002
Lymphocytes % 3 9,8 ± 10 4,9 ± 4 <0,001
NLR3 8 ± 10 18 ± 18 <0,001
CT scan parameters Highest Dimension 43 ± 21 130 ± 81 <0,001
3
Infra-hyoid Extension1 (n=64) 30,6% 90,5% <0,001
Presence of Gas1 (n=39) 16,7% 75% <0,001
Involved neck spaces 1 Peritonsillar (n=36) 20% 35% 0,247
Masticator (n=36) 24,1% 5% 0,079
Parotid (n=6) 4,1% 0% 0,610

Submandibular (n=98) 65,5% 15% <0,001
Sublingual (n=21) 14,5% 0% 0,079
Submental (n=16) 10,3% 5% 0,696
Parapharyngeal (n=68) 37,9% 65% 0,029
Retropharyngeal (n=30) 11,7% 65% <0,001
Prevertebral (n=11) 3,4% 30% <0,001
Visceral (n=29) 10,3% 70% <0,001
Location 1 Unilateral (n=134) 86,2% 45% <0,001
Bilateral (n=31) 13,8% 55%
Surgery 1 External Drainage (n=132) 79,3% 85% 0,767

Intra-oral Drainage (n=33) 20,7% 15%
1 Chi-square or Fischer’s Exact Test; presented as percentage; Student T-Test; presented as mean ± standard deviation;
2
3 Man-Whitney U test; presented as median ± interquartile range; CRP, C-reactive protein; CT, computed tomography;
NLR, neutrophil to lymphocyte ratio.

Volume 61 . Nº4 . Dezembro 2023 371